Endomorphin-2: A Biased Agonist at the μ-Opioid Receptor
نویسندگان
چکیده
منابع مشابه
Endomorphin-2: a biased agonist at the μ-opioid receptor.
Previously we correlated the efficacy for G protein activation with that for arrestin recruitment for a number of agonists at the μ-opioid receptor (MOPr) stably expressed in HEK293 cells. We suggested that the endomorphins (endomorphin-1 and -2) might be biased toward arrestin recruitment. In the present study, we investigated this phenomenon in more detail for endomorphin-2, using endogenous ...
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ژورنال
عنوان ژورنال: Molecular Pharmacology
سال: 2012
ISSN: 0026-895X,1521-0111
DOI: 10.1124/mol.112.078659